Pediatric oncology has a strong research culture. Most pediatric oncologists are investigators, involved in clinical care as well as research. As a result, a remarkable proportion of children with cancer enrolls in a trial during treatment. This paper discusses the ethical consequences of the unprecedented integration of research and care in pediatric oncology from the perspective of parents and physicians. An empirical ethical approach, combining (1) a narrative review of (primarily) qualitative studies on parents' and physicians' experiences of the pediatric (...) oncology research practice, and (2) comparison of these experiences with existing theoretical ethical concepts about (pediatric) research. The use of empirical evidence enriches these concepts by taking into account the peculiarities that ethical challenges pose in practice. Analysis of the 22 studies reviewed revealed that the integration of research and care has consequences for the informed consent process, the promotion of the child's best interests, and the role of the physician (doctor vs. scientist). True consent to research is difficult to achieve due to the complexity of research protocols, emotional stress and parents' dependency on their child's physician. Parents' role is to promote their child's best interests, also when they are asked to consider enrolling their child in a trial. Parents are almost never in equipoise on trial participation, which leaves them with the agonizing situation of wanting to do what is best for their child, while being fearful of making the wrong decision. Furthermore, a therapeutic misconception endangers correct assessment of participation, making parents inaccurately attribute therapeutic intent to research procedures. Physicians prefer the perspective of a therapist over a researcher. Consequently they may truly believe that in the research setting they promote the child's best interests, which maintains the existence of a therapeutic misconception between them and parents. Due to the integration of research and care, their different ethical perspectives become intertwined in the daily practice of pediatric oncology. Increasing awareness of what this means for the communication between parents and physicians is essential. Future research should focus on efforts that overcome the problems that the synchronicity of research and care evokes. (shrink)

We study Kim-independence over arbitrary sets. Assuming that forking satisfies existence, we establish Kim's lemma for Kim-dividing over arbitrary sets in an NSOP1 theory. We deduce symmetry of Kim-independence and the independence theorem for Lascar strong types.

In this paper, I explore links between the phenomenology-inspired philosophy of emotion, especially discussions of affective intentionality and situated affectivity, and those strands of work in the field of cultural affect studies that take their inspiration fromSpinoza and Deleuze. As bridges between these fields, I propose the concepts ‘disclosive posture’ and ‘affective arrangement’. ‘Disclosive posture’ condenses insights from phenomenological work on affectivity, especially those pertaining to what Heidegger calls Befindlichkeit. ‘Affective arrangement’ is a descendant of Deleuze and Guattari’s term agencement. (...) It refers to heterogeneous ensembles of elements coalescing into a sphere of heightened affective intensity in a local setting. I develop this notion into a tool for analyzing situated affectivity. As it does not yet figure prominently within debates in the philosophy of emotion, I will outline what is meant by ‘affective arrangement’ in some detail. Throughout, I discuss a productive tension between these two conceptual strands. (shrink)

The contemporary situation within the realm of ethical theories is quite complicated. Were it not enough that many classical ethical theories are evolving into the new modern forms, new types of ethical theories are arising, as well. The main aim of the paper is to introduce this issue of ethical theories which are known under the term hybrid ethical theories. A secondary aim of the paper is to describe and characterize the contemporary ethical theory of ethics of social consequences, and (...) look for the answer whether it can be an example of this type of theory. To achieve the scope, the paper begins with a short introduction into the issue of contemporary consequentialism, followed by a presentation of the concept of hybrid ethical theories and its examples. Later the variability of consequentialism and ethics of social consequences are presented. The normative basis of this theory is subsequently analysed and explored in the context of hybrid ethical theories. Finally, the study clarify that the ethics of social consequences might be considered as a hybrid ethical theory. (shrink)

The article outlines the distributive demands of relational equality in the form of a dynamic corridor of legitimate distributive inequality. It does so by complementing the already widely accepted sufficientarian floor with a limitarian ceiling, leading, in a first step, to a "corridor" of limited distributive inequality as a necessary condition for relational equality. This corridor alone, however, only provides necessary distributive conditions for relational equality and still allows for degrees of distributive inequality that would risk undermining egalitarian relations. Thus, (...) in a second step, intra-corridor distributive inequalities must be regulated by two further constraints: a (context- dependent) ratio between the best- and worst-off, and a demand for equality of opportunity so that inequalities result from people’s responsible choices. This set of demands spells out the distributive conditions that are not only necessary, but sufficient to provide a sound distributive basis for relational equality. After presenting this view, the article defends it against several objections. (shrink)

Antirealists who hold the knowability thesis, namely that all truths are knowable, have been put on the defensive by the Church-Fitch paradox of knowability. Rejecting the non-factivity of the concept of knowability used in that paradox, Edgington has adopted a factive notion of knowability, according to which only actual truths are knowable. She has used this new notion to reformulate the knowability thesis. The result has been argued to be immune against the Church-Fitch paradox, but it has encountered several other (...) triviality objections. Schlöder in a forthcoming paper defends the general approach taken by Edgington, but amends it to save it in turn from the triviality objections. In this paper I will argue, first, that Schlöder's justification for the factivity of his version of the concept of knowability is vulnerable to criticism, but I will also offer an improved justification that is in the same spirit as his. To the extent that some philosophers are right about our intuitive concept of knowability being a factive one, it is important to explore factive concepts of knowability that are made formally precise. I will subsequently argue that Schlöder's version of the knowability thesis overgenerates knowledge or, in other words, it leads to attributions of knowledge where there is ignorance. This fits a general pattern for the research programme initiated by Edgington. This paper also contains preliminary investigations into the internal and logical structure of lines of inquiries, which raise interesting research questions. (shrink)

We introduce a family of local ranks $D_Q$ depending on a finite set Q of pairs of the form $(\varphi (x,y),q(y)),$ where $\varphi (x,y)$ is a formula and $q(y)$ is a global type. We prove that in any NSOP $_1$ theory these ranks satisfy some desirable properties; in particular, $D_Q(x=x)<\omega $ for any finite tuple of variables x and any Q, if $q\supseteq p$ is a Kim-forking extension of types, then $D_Q(q) (...) Kim-non-forking extension, then $D_Q(q)=D_Q(p)$ for every Q that involves only invariant types whose Morley powers are -stationary. We give natural examples of families of invariant types satisfying this property in some NSOP $_1$ theories.We also answer a question of Granger about equivalence of dividing and dividing finitely in the theory $T_\infty $ of vector spaces with a generic bilinear form. We conclude that forking equals dividing in $T_\infty $, strengthening an earlier observation that $T_\infty $ satisfies the existence axiom for forking independence.Finally, we slightly modify our definitions and go beyond NSOP $_1$ to find out that our local ranks are bounded by the well-known ranks: the inp-rank (burden), and hence, in particular, by the dp-rank. Therefore, our local ranks are finite provided that the dp-rank is finite, for example, if T is dp-minimal. Hence, our notion of rank identifies a non-trivial class of theories containing all NSOP $_1$ and NTP $_2$ theories. (shrink)

Due to the intense selection pressure against inbreeding, humans are expected to possess psychological adaptations that regulate mate choice and avoid inbreeding. From a gene’s-eye perspective, there is little difference in the evolutionary costs between situations where an individual him/herself is participating in inbreeding and inbreeding among other close relatives. The difference is merely quantitative, as fitness can be compromised via both routes. The question is whether humans are sensitive to the direct as well as indirect costs of inbreeding. Using (...) responses from a large population-based sample (27,364 responses from 2,353 participants), we found that human motivations to avoid inbreeding closely track the theoretical costs of inbreeding as predicted by inclusive-fitness theory. Participants were asked to select in a forced choice paradigm, which of two acts of inbreeding with actual family members they would want to avoid most. We found that the estimated fitness costs explained 83.6% of participant choices. Importantly, fitness costs explained choices also when the self was not involved. We conclude that humans intuit the indirect fitness costs of mating decisions made by close family members and that psychological inbreeding avoidance mechanisms extend beyond self-regulation. (shrink)

Of all the attitudes and theories associated with or identified as "pacifism," only the doctrine that everyone ought not to resist violence with force is of philosophical interest, And it is logically incoherent. Pacifism's popularity rests on confusions about what the doctrine really is. If we have rights, We have the right to prevent infringements upon them. We have the right to use force to protect our rights, And in the degree necessary to accomplish that end. (staff).

This paper discusses the presentation of the Epicurean virtues offered in the Letter to Menoeceus and in Cicero’s On Ends. It evaluates the proposals advanced by Phillip Mitsis and Pierre-Marie Morel. Against Morel, it is argued that Torquatus’ presentation of the virtues in On Ends is not part of an elaborate dialectical strategy. Instead, the paper sides with Mitsis’ more modest proposal: while Torquatus, like any good speaker, with high likelihood adapts his presentation to his audience, his ideas also have (...) a strong foundation in Epicureanism. Given the extant state of textual evidence, it is difficult to determine precisely, however, to what degree his presentation of the virtues (1) directly draws on ideas already present in the founder of the Garden himself, (2) reflects a later development in the Epicurean school, or (3) falsifies Epicurean ideas to make them more palatable for a Roman audience. (shrink)

This paper aims to contribute to the expanding discourse on inter- and transdisciplinarity. Referring to well-established distinctions in philosophy of science, the paper argues in favor of a plurality of four different dimensions: Interdisciplinarity with regard to objects, knowledge/theories, methods/practices, and further, problem perception/problem solving. Different philosophical thought traditions can be related to these distinguishable meanings. The philosophical framework of the four different dimensions will be illustrated by some of the most popular examples of research programs that are labeled interdisciplinary (...) : nanoresearch/nanoscience/nanotechnology, complex systems theory/chaos theory, biomimicry/bionics, and technology assessment/sustainability research. Thus, a minimal philosophy of science is required to understand and foster inter- and transdisciplinarity. (shrink)

INTRODUCTION This study arose from involvement with the works of Thomas Aquinas (/5-) that was not only intensive, but also extensive in the time devoted to ...

In "De malorum subsistentia" chs 30-7, Proclus criticizes the view that evil is to be identified with matter. His main target is Plotinus' account in Enn. I,8 [51]. Proclus denies that matter is the cause of evil in the soul, and that it is evil or a principle of evil. According to Proclus, matter is good, because it is produced by the One. Plotinus' doctrine of matter-evil is the result of a different conception of emanation, according to which matter does (...) not revert to its principle. Proclus claims that to posit a principle of evil either amounts to a coarse dualism, or makes the Good ultimately responsible for evil. Plotinus does not seem to be able to escape the latter consequence, if he is to remain committed to the Neoplatonic conception of causation. Plotinus equated matter with privation and said it is a kind of non-being that is the contrary of substance, thus violating fundamental Aristotelian tenets. Proclus reinstates Aristotelian orthodoxy, as does Simplicius in his "Commentary on the Categories." It is possible that lamblichus was the source of both Proclus and Simplicius, and that he was the originator of the parhypostasis theory and the inventor of the anti-Plotinian arguments. (shrink)

One can often encounter an opinion that Polish scientific philosophy deserves to be much better known than actually is. This book is thought as a response to such a claim. The papers collected in this volume are divided into two parts: Background and Influence and History and Systematics. However, there is no sharp borderline between themes which are touched in both parts. Generally speaking, all papers of the first part relate the Lvov-Warsaw School to some philosophical movements external to it (...) whereas the papers collected in the second one focus on internal issues connected with the school . Since the Polish school of mathematical logic is much better known than the Polish analytic philosophy we decided to omit here any treatment of the former. Thus, this collection centers on purely philosophical matters. We projected this volume not as an exhaustive panorama of Polish analytic philosophy but rather as a series of essays on particular persons or topic. As a result one can find here papers on Twardowski. Ajdukiewicz, Kotarbinski, Tarski and Lukasiewicz as well as on ethics on science, nominalism, and the methodology of psychology. We hope that this book will contribute to a better knowledge and evaluation of Polish achievements in analytic philosophy. We would like to express our gratitude to Professor Leszek Nowak, the editor-in-chief of Poznan Studies in the Philosophy of the Sciences and the Humanities, who initiated the idea of the collection and helped in its preparation. (shrink)

How do states build a security apparatus after violent resistance against state rule? This article argues that in early periods of state building two main factors shape the process: the macro-strategic goals of the state and administrative challenges of personnel management. These dynamics are studied in the context of the establishment of police forces in the settler colony of German Southwest Africa, present-day Namibia. The empirical analysis relies on information about the location of police stations and a near full census (...) of police forces, compiled from the German Federal Archives. A mismatch is found between the allocation of police presence and the allocation of police personnel. The first was driven by the strategic value of locations in terms of extractive potential, political importance, and the presence of critical infrastructure, whereas the allocation of individual officers was likely affected by adverse selection, which led to the assignment of low-quality recruits to strategically important locations. (shrink)

As privacy concerns among consumers rise, service providers increasingly want to provide services that support privacy enhancing technologies. At the same time, online service providers must be able to protect themselves against misbehaving users. For instance, users that do not pay their bill must be held accountable for their behavior. This tension between privacy and accountability is fundamental, however a tradeoff is not always required. In this article we propose the concept of a time capsule, that is, a verifiable encryption (...) with timed and revocable decryptability. The time capsule together with its related protocols offer support of privacy while retaining strong accountability. In our scheme an honest user may enjoy full anonymity, but dishonest users who do not pay their bill have their identity revealed. In contrast to existing revocable anonymity systems, our proposed scheme requires less trust in an external authority, while simultaneously making accountability easier (and less costly) to achieve. (shrink)

This article is a discussion of the instrumentalization of Martin Luther by German historiography in the nineteenth and twentieth centuries for politically‐legitimating, purpose providing and especially national purposes. In the nineteenth century the Luther jubilee of 1883 was one of the highlights of German nationalism, which had developed rapidly since the unification of 1871. During the First and Second World War Luther again was turned into an active supporter of German nationalism. This study focuses on the last large‐scale attempt to (...) instrumentalize Luther for national purposes; ie the Luther interpretation in the German Democratic Republic. With the help of a new Luther reception the GDR tried to improve the basis for her own national identity. She intensified her policy of delimitation from the Federal Republic of Germany with the help of a new and very positive Luther image. These East German attempts, however, backfired and were counter productive in their results. The political appeal to an all‐German historical personality like Martin Luther could not legitimate a divided Germany. On the contrary, it brought about the opposite, that is it rather stimulated underlying all‐German affinities and cohesive forces. Of course East German historians did not aim at “Wiedervereinigung”– which, naturally was a political issue of the highest degree. But, with the aid of Luther, they unconsciously played an important part in setting the stage for German unification. (shrink)

Článek spadá do tematické oblasti současných snah o oživení Aristotelovy etické teorie. V užším vymezení jde o téma aktualizace konceptu morálního charakteru (či mravní ctnosti), které je spojováno s využitím poznatků psychologických věd. Zde pak klíčovou pozornost věnuji problému kritérií, podle kterých můžeme posuzovat adekvátnost návrhů na takovou aktualizaci. Vedle běžně respektovaných kritérií interdisciplinarity a empirické a normativní adekvátnosti představuji kritérium funkce, které je ústředním pojmem článku. Cílem článku je formulovat toto kritérium a pro jeho vyjasnění co nejlépe vystihnout funk­ci (...) (zjednodušeně řečeno užitečnost či přínos) Aristotelovy etické teorie. Dále je mým zámě­rem na příkladech představit, jaké důsledky by mělo přijetí tohoto kritéria (tedy zachování či zefektivnění funkce) pro posuzování adekvátnosti návrhů k aktualizaci Aristotelova konceptu morálního charakteru. Za funkci Aristotelovy etické teorie považuji zvyšování naší morální gramotnosti a tvrdím, že tato funkce vyplývá ze stěžejního rysu Aristotelovy práce, z důsledné analýzy a nalezení vzájemných vazeb mezi pojmy, které spojujeme s každodenní morálkou a s prožíváním dob­rého a spokojeného života. Na konkrétních příkladech ukazuji, jak snahy naplnit jiná kritéria adekvátní aktualizace mohou vést k pojmové redukci, zahlcení irelevantními informacemi, nebo jinak narážet na kritérium funkce. Naplnění všech zde představených kritérií ilustruji na analogii dovednosti, kterou jakožto aktualizaci představila Julia Annasová. (shrink)

In this paper I fix a typical regress argument, locate a typical gap in the argument, and try to supply a number of gap-filling readings of its first premise.

At the end of Book 15 of his Res Gestae Ammianus Marcellinus reports how Strategius Musonianus became the successor of the murdered Domitianus as Praefectus Praetorio Orientis . He tells that Strategius was a man versed in the two languages, i.e. Greek and Latin, and that because of this he had won a higher distinction than was expected. When Constantine the Great, so says Ammianus, was looking for an expert interpreter for his investigation into the Manichaean and similar heresies, he (...) chose Strategius as a person recommended to him as competent. Constantine was so pleased with Strategius' skilful work that he gave him the honourable nickname Musonianus, which became his official name. This assignment was the start of a great career which eventually led to his denomination as PPO under Constantius II. (shrink)

This volume weaves together a variety of perspectives aimed at confronting a spectrum of ethico-political global challenges arising in the Anthropocene which affect the future of life on planet earth. In this book, the authors offer a multi-faceted approach to address the consequences of its imaginary and projective directions. The chapters span the disciplines of political economy, cybernetics, environmentalism, bio-science, psychoanalysis, bioacoustics, documentary film, installation art, geoperformativity, and glitch aesthetics. The first section attempts to flesh out new aspects of current (...) debates. Questions over the Capitaloscene are explored via conflations of class and climate, revisiting the eco-Marxist analysis of capitalism, and the financial system that thrives on debt. The second section explores the imaginary narratives that raise questions regarding non-human involvement. The third section addresses ’geoartisty,’ the counter artistic responses to the speculariztion of climate disasters, questioning eco-documentaries, and what a post-anthropocentric art might look like. The last section addresses the pedagogical response to the Anthropocene. (shrink)

In this volume specialists of medieval music and philosophy put the medieval 'musica' into the context of ideas and institutions in which it existed. The significance of 'musica' cannot be understood from a modern point of view since 'music' does not match the medieval 'musica'.

Cílem článku je prozkoumat otázku po epistemickém statusu morálních intuic. Empirické výzkumy na poli morální psychologie ukazují, že intuice hojně využíváme při morálním hodnocení. Spoléháme se na ně však i jako morální filosofové při testování našich teorií – má-li některá normativní teorie proti-intuitivní důsledky, chápeme to jako její vadu a vice versa. V článku se snažím zodpovědět otázku, zda je taková praxe odvolávání se na morální intuice jako na evidenci ospravedlnitelná – je morální intuice spolehlivým epistemickým kanálem? Nejprve se budu (...) opírat o příbuznou debatu zaměřenou na epistemické intuice, představím tzv. restrikcionistickou výzvu a vysvětlím, z jakého důvodu se zaměřuji na morální intuice. V následující sekci předložím dle mého názoru nejsilnější linii útoku na epistemickou spolehlivost morálních intuic – argument z intuitivní nestability. Dříve jsme nevycházeli z úžasu nad zprávami o masivních rozdílech mezi námi Zápaďany a obyvateli exotických krajin, kterými nás ze svých terénních výzkumů zásobovali etnografové a antropologové. Dnes to jsou především morální psychologové a experimentální filosofové, kteří nás udivují ještě více odhalováním značné variability v intuicích – tentokrát však nejen mezi civilizovanými a domorodými lidmi, nýbrž i v srdci naší vlastní kultury. V další části tak předložím jednoduchou typologii intuitivní nestability a představím v současnosti již značně rozsáhlý soubor dat, který dokumentuje právě tuto neblahou vlastnost morálních intuic. Na jejich základě pak ve finální sekci dospěji k závěru, že morální intuice nejsou schopné dostát epistemickým nárokům, které klademe na jiné informační zdroje (např. smyslové vnímání), a jako takové nemohou sehrávat svou domnělou evidenční roli. V úplném závěru předložím předběžné poznámky týkající se možnosti využívat morálních intuic spíše jako zdroje motivace a za tím účelem navrhnu obrátit filosofickou praxi testování normativních teorií naruby. (shrink)

The article investigates how two different conceptions of the edifying potential of education attempt to take into account the normative dimension of scientific knowledge. In the first conception it is the demand for truth that is edifying, whereas in the second concept it is a distinctively ethical demand. It is argued that the first concept in the end implies the subjection of education to the ‘brutality of facticity’, under which it risks losing its critical point. The second conception, drawing on (...) Levinas and Arendt, tries to safeguard this critical point. It conceives education as a process through which scientific knowledge is made subject to reflection, and is thus confronted with the ethical challenges and demands of society. (shrink)

It was not only in his infamous speeches as NSDAP-approved Führer- Rektor of Freiburg University that Heidegger advocated what can be seen as an ‘activist’ understanding of human existence. To exist, according to this approach, means to be called upon to take charge of one’s life - actively, responsibly, authentically - whether mandated by Volk and Führer or not. Heideggerian resoluteness amounts to being active in a deep sense, a view articulated during the Rektoratszeit in the form of an outright (...) equation of dasein and work. I will revisit Heidegger’s phenomenology of boredom in Basic Concepts of Metaphysics, and contrast it with passages from Fernando Pessoa’s Book of Disquiet. Pessoa presents a radical counterpoint to Heidegger, utterly at odds with his intellectual and political persona. Insofar as the early Heidegger still represents the sinister forces ruling on the death star of western metaphysics, Pessoa carries the light that can set us on a path toward very different horizons for thinking being. (shrink)